Description

N(6)-Methoxyadenosine is a chemically modified nucleoside derivative of adenosine, featuring a methoxy group at the N6 position of the adenine base. This structural modification makes it a valuable intermediate and reference standard in pharmaceutical research and development, particularly for studying adenosine receptor activity and metabolic pathways. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications in medicinal chemistry, biochemical research, and as a building block for novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel adenosine receptor agonists, antagonists, and other nucleoside-based therapeutics.
• Biochemical Research: Used as a reference standard and tool compound in enzymatic studies, metabolic pathway analysis, and receptor-ligand binding assays.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Academic Research: Employed in university and institutional labs for fundamental research in nucleoside chemistry, epigenetics, and signal transduction.
• Standards & Calibration: Provides a high-purity analytical standard for quality control and method validation in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	N(6)-Methoxyadenosine
CAS No.	19399-25-8
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	6-Methoxyadenosine; N6-Methoxyadenosine; Adenosine, N(6)-methyl ether; 6-Methoxy-9-β-D-ribofuranosyl-9H-purine; 6-Methoxy-9-β-D-ribofuranosyladenine; 9-β-D-Ribofuranosyl-6-methoxy-9H-purine; 6-Methoxy-9-(β-D-ribofuranosyl)adenine
EINECS	Contact for details

Quality Control

Our N(6)-Methoxyadenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.