Description

2-Biphenyl Isothiocyanate is a specialized organic building block featuring a biphenyl core functionalized with a reactive isothiocyanate group. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocyclic compounds and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those with biphenyl scaffolds, for therapeutic areas like oncology and CNS disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the biphenyl moiety can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing material properties for advanced coatings or adhesives.
• Chemical Biology Probe Synthesis: Useful for creating isothiocyanate-based probes for labeling and studying proteins or other biomolecules.
• Organic Electronic Material Research: Investigated as a component in the development of organic semiconductors and light-emitting materials.

Basic Information

Product Name	2-Biphenyl Isothiocyanate
CAS No.	19394-61-7
Molecular Formula	C₁₃H₉NS
Molecular Weight	211.28 g/mol
Synonyms	[1,1'-Biphenyl]-2-yl isothiocyanate; 2-Isothiocyanatobiphenyl; o-Biphenyl isothiocyanate; 2-Biphenylyl isothiocyanate; NSC 163045; Biphenyl-2-isothiocyanate; 2-Phenylphenyl isothiocyanate
EINECS	Contact for details

Quality Control

Our 2-Biphenyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.