Description

6-Chlorohexanoyl Chloride is a versatile bifunctional organic intermediate featuring both a reactive acid chloride group and a terminal chloroalkyl chain. This compound matters for its role as a key building block in the synthesis of complex molecules, enabling the introduction of a six-carbon spacer with a modifiable end group. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing active pharmaceutical ingredients (APIs), liquid crystal monomers, and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those requiring a lipophilic carbon chain linker, such as certain protease inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the chlorohexanoyl moiety is incorporated into the active molecule.
• Liquid Crystal Manufacturing: Serves as a starting material for synthesizing mesogenic compounds and monomers used in display technologies.
• Polymer & Material Science: Employed to create functionalized polymers, dendrimers, and surface-modifying agents through reactions with alcohols or amines.
• Cross-linking Agent: Acts as a difunctional linker in peptide synthesis and for conjugating molecules in bioconjugation applications.
• Organic Synthesis Reagent: Utilized in Friedel-Crafts acylation and other acylations to introduce the 6-chlorohexanoyl group into aromatic and heterocyclic systems.

Basic Information

Product Name	6-Chlorohexanoyl Chloride
CAS No.	19347-73-0
Molecular Formula	C6H10Cl2O
Molecular Weight	169.05 g/mol
Synonyms	6-Chlorohexanoic acid chloride; 6-Chlorohexanoyl chloride; Hexanoyl chloride, 6-chloro-; 6-Chlorocaproyl chloride; ω-Chlorohexanoyl chloride; Caproyl chloride, 6-chloro-; 1-Chloro-6-chloroformylhexane; 19347-73-0
EINECS	242-974-6

Quality Control

Our 6-Chlorohexanoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including GC, HPLC, and NMR to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, alcohols, and amines. Recommended storage temperature is 2-8°C for long-term stability. The product is moisture-sensitive; keep container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.