Description

4-Bromo-2-Methylphenyl Isothiocyanate is a versatile organosulfur compound featuring a reactive isothiocyanate group attached to a brominated and methylated aromatic ring. This molecular structure makes it a valuable key synthetic intermediate for constructing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, crop protection, and polymer synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromine and isothiocyanate functionalities enable specific biological activity.
• Chemical Research & Development: Acts as a versatile reagent for heterocyclic chemistry, enabling the construction of thiazole, thiourea, and other sulfur-containing heterocycles.
• Material Science Precursor: Employed in the development of specialty polymers, liquid crystals, and functional materials that require specific aromatic and sulfur-based components.
• Ligand and Catalyst Development: Utilized for creating novel ligands for metal-organic frameworks (MOFs) or catalysts due to its ability to coordinate with various metal ions.

Basic Information

Product Name	4-Bromo-2-Methylphenyl Isothiocyanate
CAS No.	19241-38-4
Molecular Formula	C8H6BrNS
Molecular Weight	228.11 g/mol
Synonyms	2-Methyl-4-bromophenyl isothiocyanate; 1-Bromo-4-isothiocyanato-3-methylbenzene; 4-Bromo-o-tolyl isothiocyanate; (4-Bromo-2-methylphenyl)isothiocyanate; 2-Methyl-4-bromophenyl mustard oil; Isothiocyanic acid, 4-bromo-2-methylphenyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-Methylphenyl Isothiocyanate adheres to stringent in-process controls and final batch testing to ensure high purity and lot-to-lot consistency. Quality is verified against established internal specifications using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.