Description

4-tert-Butylphenyl Isothiocyanate is a specialized organic building block characterized by its reactive isothiocyanate functional group attached to a sterically hindered aromatic ring. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, life science, and material science industries for constructing novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those containing thiourea or related heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its bio-active potential.
• Ligand and Chelating Agent Precursor: Acts as a starting material for creating specialized ligands used in catalysis and metal complexation studies.
• Polymer Modification: Employed to introduce functional groups into polymer chains to alter material properties like adhesion, compatibility, or reactivity.
• Chemical Biology Probe Development: Utilized in bioconjugation chemistry to label proteins or other biomolecules for study and detection.
• Organic Synthesis Building Block: A versatile reagent for constructing complex organic molecules in academic and industrial research settings.

Basic Information

Product Name	4-tert-Butylphenyl Isothiocyanate
CAS No.	19241-24-8
Molecular Formula	C11H13NS
Molecular Weight	191.29 g/mol
Synonyms	p-tert-Butylphenyl Isothiocyanate; 1-Isothiocyanato-4-tert-butylbenzene; 4-(1,1-Dimethylethyl)phenyl Isothiocyanate; 4-tert-Butylphenyl Mustard Oil; NSC 403119; 4-tert-Butylbenzenisothiocyanate; p-tert-Butylbenzenisothiocyanate; 4-(tert-Butyl)phenyl Isothiocyanate
EINECS	242-904-8

Quality Control

Our 4-tert-Butylphenyl Isothiocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and incompatible materials such as amines, alcohols, and oxidizing agents. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.