Description

α-Bromophenylacetyl Chloride is a versatile and highly reactive organic intermediate, primarily used as a key building block in the synthesis of complex molecules. Its value lies in its ability to introduce the α-bromophenylacetyl moiety, a crucial structural component for imparting specific biological activity. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it serves as a precursor for active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of central nervous system (CNS) agents and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the bromophenyl group enhances efficacy.
• Peptide Mimetics & Modifications: Employed to incorporate non-natural amino acid analogs into peptides, altering their stability and biological properties for research.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Utilized in the development of specialty polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	α-Bromophenylacetyl Chloride
CAS No.	19078-72-9
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	2-Bromo-2-phenylacetyl chloride; α-Bromophenylacetyl chloride; (2-Bromo-2-phenyl)acetyl chloride; 2-Bromo-2-phenylethanoyl chloride; Bromophenylacetic acid chloride; NSC 404082; Phenacyl bromide, acid chloride; ω-Bromophenylacetyl chloride
EINECS	Contact for details

Quality Control

Our α-Bromophenylacetyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We adhere to current Good Manufacturing Practices (cGMP) where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.