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3-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-3H-Purin-6-Amine CAS NO 19046-81-2


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CAS No.:19046-81-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-3H-Purin-6-Amine is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis and study of modified oligonucleotides and nucleotide analogs. It is essential for researchers and manufacturers in the fields of antiviral drug development, oncology research, and molecular diagnostics, where precise chemical structure and purity are paramount for reliable experimental and production outcomes.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
  • Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway analysis.
  • Oligonucleotide Synthesis: Serves as a modified building block for creating specialized DNA/RNA probes and primers.
  • Antiviral Drug Development: Investigated for its potential incorporation into prodrugs targeting viral polymerases.
  • Oncology Research: Employed in the development of chemotherapeutic agents that interfere with DNA replication in cancer cells.
  • Diagnostic Reagent Manufacturing: Utilized in the production of high-specificity diagnostic kits and assays.

Basic Information

Product Name 3-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-3H-Purin-6-Amine
CAS No. 19046-81-2
Molecular Formula C₁₀H₁₃N₅O₃
Molecular Weight 251.24 g/mol
Synonyms 2'-Deoxyadenosine; Deoxyadenosine; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine; Adenine deoxyriboside; dA; 2'-dA; 2'-Deoxy-D-adenosine; 2'-Deoxyadenosine (VAN)
EINECS 242-799-9

Quality Control

Every batch of our 3-(2-Deoxy-α-D-Erythro-Pentofuranosyl)-3H-Purin-6-Amine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥98.0%
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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