Description

5-Hydroxycholestan-4-One is a high-purity steroidal ketone derivative, serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a functionalized cholestane backbone for the research and development of novel bioactive compounds. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on steroid chemistry, drug discovery, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and enzyme inhibition assays.
• Organic Synthesis: Serves as a versatile chiral starting material for constructing complex molecular architectures in medicinal chemistry.
• Academic & Industrial R&D: Fundamental compound for investigating structure-activity relationships (SAR) and developing new chemical entities.

Basic Information

Product Name	5-Hydroxycholestan-4-One
CAS No.	19043-66-4
Molecular Formula	C₂₇H₄₆O₂
Molecular Weight	402.66 g/mol
Synonyms	4-Cholestanone, 5-hydroxy-; 5-Hydroxy-4-cholestanone; 5-Hydroxycholest-4-one; 5-Hydroxy-cholestan-4-one; 4-Cholestanone, 5-hydroxy- (8CI); 5-Hydroxy-4-cholestan-4-one; 5-Hydroxy-4-cholestanone (VAN)
EINECS	Contact for details

Quality Control

Our 5-Hydroxycholestan-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting research-grade standards. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.