Description

Methyl 3-Isothiocyanatopropionate is a versatile bifunctional organic compound containing both an isothiocyanate and an ester group. This unique structure makes it a valuable building block in organic synthesis, particularly for the preparation of heterocycles and functionalized molecules. It is primarily used by pharmaceutical intermediates manufacturers and agrochemical research and development teams.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thiourea or heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile reagent for constructing molecular libraries and exploring new synthetic pathways in medicinal chemistry.
• Polymer Modification: Can act as a cross-linking agent or functional monomer for specialty polymers and coatings.
• Bioconjugation Chemistry: The reactive isothiocyanate group allows for coupling with amines, useful in labeling and probe development.

Basic Information

Product Name	Methyl 3-Isothiocyanatopropionate
CAS No.	18967-35-6
Molecular Formula	C5H7NO2S
Molecular Weight	145.18 g/mol
Synonyms	Methyl 3-isothiocyanatopropanoate; 3-Isothiocyanatopropionic Acid Methyl Ester; Methyl β-Isothiocyanatopropionate; NSC 3349; Methyl 3-isothiocyanopropionate; Propanoic acid, 3-isothiocyanato-, methyl ester
EINECS	242-728-7

Quality Control

Our Methyl 3-Isothiocyanatopropionate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP for intermediate production and is compliant with global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.