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3β-[[6-Deoxy-4-o-(6-Deoxy-α-L-Mannopyranosyl)-α-L-Mannopyranosyl]Oxy]-14-Hydroxybufa-4,20,22-Trienolide CAS NO 18894-18-3


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CAS No.:18894-18-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[[6-Deoxy-4-o-(6-Deoxy-α-L-Mannopyranosyl)-α-L-Mannopyranosyl]Oxy]-14-Hydroxybufa-4,20,22-Trienolide is a high-purity, specialized cardiac glycoside compound derived from natural sources. This product is critical for pharmaceutical research and development, particularly in the study of cardiac pharmacology and the development of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in advanced medicinal chemistry and drug discovery programs.

Application

  • Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
  • Cardiac Drug Research: A key intermediate and active pharmaceutical ingredient (API) precursor in the research of heart failure medications and inotropic agents.
  • Biochemical Research: Used in pharmacological studies to investigate mechanisms of action related to Na+/K+-ATPase inhibition.
  • Natural Product Chemistry: Employed as a standard for the isolation, identification, and quantification of related bufadienolides in complex natural extracts.
  • Academic Research: Utilized in university and institutional labs for teaching and advanced research in medicinal chemistry and pharmacology.
  • Preclinical Development: Acts as a lead compound or a chemical probe in the early stages of new drug candidate development.

Basic Information

Product Name 3β-[[6-Deoxy-4-o-(6-Deoxy-α-L-Mannopyranosyl)-α-L-Mannopyranosyl]Oxy]-14-Hydroxybufa-4,20,22-Trienolide
CAS No. 18894-18-3
Molecular Formula C36H52O13
Molecular Weight 692.79 g/mol
Synonyms 14-Hydroxy-3β-[(6-deoxy-4-O-α-L-rhamnopyranosyl-α-L-mannopyranosyl)oxy]bufa-4,20,22-trienolide; Bufalin 3-rhamnosylmannoside; Bufotalin glycoside; Scillarenin analog; Cardiac glycoside C36H52O13; 18894-18-3; Bufadienolide glycoside
EINECS Contact for details

Quality Control

Our 3β-[[6-Deoxy-4-o-(6-Deoxy-α-L-Mannopyranosyl)-α-L-Mannopyranosyl]Oxy]-14-Hydroxybufa-4,20,22-Trienolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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