Description

Corticosterone 21-[3-(Sodiooxycarbonyl)Propanoate] is a chemically modified derivative of the endogenous glucocorticoid corticosterone, designed for enhanced stability and specific reactivity. This compound is a critical intermediate in the synthesis of more complex steroid conjugates and labeled compounds for research and diagnostic applications. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions engaged in endocrinology and metabolic studies.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of corticosterone-protein conjugates used in immunoassay development.
• Diagnostic Reagent Production: Essential for manufacturing antigens and calibrators in ELISA and RIA kits for stress hormone detection.
• Biochemical Research: Used as a precursor in metabolic pathway studies and for creating molecular probes to investigate glucocorticoid receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control in steroid hormone analysis via HPLC or LC-MS.
• Tracer Synthesis: Facilitates the production of radiolabeled (e.g., tritiated) or fluorescently tagged corticosterone analogs for binding assays.

Basic Information

Product Name	Corticosterone 21-[3-(Sodiooxycarbonyl)Propanoate]
CAS No.	18843-27-1
Molecular Formula	C25H33NaO7
Molecular Weight	468.52 g/mol
Synonyms	Corticosterone 21-Hemisuccinate Sodium Salt; Corticosterone 21-Succinate Sodium Salt; 11β,21-Dihydroxypregn-4-ene-3,20-dione 21-(3-Carboxypropanoate) Sodium Salt; B-Succ Sodium Salt; Corticosterone 21-Hemisuccinate Na; 21-HSC Sodium Salt; Corticosterone-21-yl hydrogen succinate sodium salt
EINECS	Contact for details

Quality Control

Our Corticosterone 21-[3-(Sodiooxycarbonyl)Propanoate] is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.