Description

1H-1,2,3-Triazole-4-Carbonitrile is a versatile heterocyclic building block and key synthetic intermediate prized for its bifunctional reactivity. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral, anticancer, and anti-inflammatory drug candidates, leveraging the triazole and nitrile functionalities for further derivatization.
• Agrochemical Synthesis: Used in the production of novel fungicides, herbicides, and plant growth regulators where the triazole core provides essential biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalytic processes.
• Material Science: Employed in the research and development of polymers, dyes, and photoactive materials due to its ability to incorporate into larger conjugated systems.
• Chemical Biology & Proteomics: Acts as a click chemistry component or a bioisostere in probe and tool molecule synthesis for studying biological systems.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	1H-1,2,3-Triazole-4-Carbonitrile
CAS No.	18755-49-2
Molecular Formula	C3H2N4
Molecular Weight	94.07 g/mol
Synonyms	4-Cyano-1H-1,2,3-triazole; 1H-1,2,3-Triazole-4-carbonitrile; 4-Cyano-1,2,3-triazole; 1,2,3-Triazole-4-carbonitrile; 4-CN-1H-1,2,3-triazole; 4-Cyanotriazole
EINECS	Contact for details

Quality Control

Our 1H-1,2,3-Triazole-4-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.