Description

8-Benzyl-8-Azabicyclo[3.2.1]Octan-3-Endo-Ol is a specialized bicyclic amine derivative, serving as a crucial advanced pharmaceutical intermediate. Its value lies in its unique stereochemistry and functional groups, which make it a versatile building block for complex organic synthesis. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tropane alkaloid derivatives and other bioactive molecules targeting the central nervous system.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce the rigid 8-azabicyclo[3.2.1]octane scaffold with defined stereochemistry (endo configuration).
• Medicinal Chemistry Research: Employed in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Intermediate for developing novel crop protection agents with specific biological activity.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	8-Benzyl-8-Azabicyclo[3.2.1]Octan-3-Endo-Ol
CAS No.	18717-73-2
Molecular Formula	C₁₅H₂₁NO
Molecular Weight	231.33 g/mol
Synonyms	3-endo-Hydroxy-8-benzyl-8-azabicyclo[3.2.1]octane; 8-Benzyl-3-endo-hydroxy-8-azabicyclo[3.2.1]octane; 8-Benzylnortropan-3-endo-ol; 3-endo-Hydroxy-8-benzylnortropane; Nortropine benzyl ether (endo isomer); 18717-73-2; endo-8-Benzyl-8-azabicyclo[3.2.1]octan-3-ol
EINECS	Contact for details

Quality Control

Our 8-Benzyl-8-Azabicyclo[3.2.1]Octan-3-Endo-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.