Description

(3Beta,5Beta)-3-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide CAS NO 18695-02-8 is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and structural complexity, which are essential for studying cardiac activity and developing novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on cardiovascular pharmacology and natural product synthesis.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Cardiovascular Research: Used as a key biochemical tool to investigate the mechanisms of cardiac glycosides and their interaction with Na+/K+-ATPase.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a crucial synthetic intermediate in the production of specialized cardiac medications.
• Natural Product Chemistry Studies: Employed in research to understand the structure-activity relationships of complex steroid-based natural products.
• Analytical Method Development: Utilized for calibrating HPLC, LC-MS, and other chromatographic systems in analytical laboratories.
• Preclinical Studies: Used in in-vitro and in-vivo studies to evaluate pharmacological potency and toxicological profiles.

Basic Information

Product Name	(3Beta,5Beta)-3-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide
CAS No.	18695-02-8
Molecular Formula	C29H44O9
Molecular Weight	536.66 g/mol
Synonyms	Digitoxigenin β-D-digitoxoside; 3β-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-5β,14β,19-trihydroxycard-20(22)-enolide; Strophanthidin β-D-digitoxoside; 3β-(Digitoxosyloxy)-5β,14β,19-trihydroxycard-20(22)-enolide; 18695-02-8; Cardiac glycoside intermediate; Digitoxigenin digitoxoside
EINECS	Contact for details

Quality Control

Our (3Beta,5Beta)-3-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.