Description

Cytidine, 5'-Acetate is a key acetylated derivative of the nucleoside cytidine, specifically modified at the 5'-hydroxyl position. This chemical modification is crucial for enhancing lipophilicity and controlling reactivity in advanced synthetic pathways, making it a valuable building block. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications including oligonucleotide synthesis, prodrug development, and biochemical research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a protected monomer in the solid-phase synthesis of DNA and RNA sequences for research and therapeutic applications.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and nucleotide processing.
• Prodrug Development: The acetyl group can be utilized as a cleavable promoiety to improve the bioavailability and targeting of nucleoside-based drugs.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC or LC-MS methods.

Basic Information

Product Name	Cytidine, 5'-Acetate
CAS No.	18531-23-2
Molecular Formula	C11H15N3O5
Molecular Weight	269.25 g/mol
Synonyms	5'-O-Acetylcytidine; Cytidine 5'-acetate; 1-(5-O-Acetyl-β-D-ribofuranosyl)cytosine; 5'-Acetylcytidine; N4-Amino-1-(5-O-acetyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone; Cytidine, 5'-monoacetate
EINECS	Contact for details

Quality Control

Our Cytidine, 5'-Acetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.