Description

9-(3,4,5-Trihydroxyoxan-2-Yl)-3H-Purin-6-One is a purine nucleoside derivative of significant interest in advanced biochemical and pharmaceutical research. This compound serves as a crucial building block and reference standard for the development of novel therapeutic agents and diagnostic tools. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in nucleoside chemistry, antiviral research, and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic pathway analysis, and cellular biology research.
• Life Science Reagents: Incorporated into specialized cell culture media and diagnostic kits for studying purine metabolism and related disorders.
• Academic & Industrial R&D: Serves as a critical material for exploring novel chemical modifications and structure-activity relationships (SAR) in medicinal chemistry projects.

Basic Information

Product Name	9-(3,4,5-Trihydroxyoxan-2-Yl)-3H-Purin-6-One
CAS No.	18520-88-2
Molecular Formula	C10H12N4O5
Molecular Weight	268.23 g/mol
Synonyms	6-Hydroxy-9-β-D-ribofuranosylpurine; Nebularine; Purine-6-ol, 9-β-D-ribofuranosyl-; 9-β-D-Ribofuranosyl-9H-purin-6-ol; 9H-Purin-6-ol, 9-β-D-ribofuranosyl-; 6-Hydroxypurine riboside; Ribosylpurine-6-ol
EINECS	242-391-9

Quality Control

Our 9-(3,4,5-Trihydroxyoxan-2-Yl)-3H-Purin-6-One is produced under a strict quality management system to ensure batch-to-batch consistency and reliability for research and development purposes. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.