Description

1-(β-D-Xylofuranosyl)-5-Methylcytosine is a modified nucleoside analog, a key building block in nucleic acid chemistry and medicinal research. This compound is valued for its role in the synthesis of oligonucleotides with specific structural and functional properties, enabling advanced biochemical studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic probes, and molecular biology tools.

Application

• Oligonucleotide Synthesis: A critical precursor for the solid-phase synthesis of modified DNA and RNA strands, particularly for introducing site-specific methylation patterns.
• Antiviral & Anticancer Research: Serves as a scaffold in the development of nucleoside-based prodrugs and therapeutic agents targeting viral replication and cellular proliferation.
• Epigenetics Studies: Used to investigate DNA methylation processes and their role in gene expression regulation, a cornerstone of epigenetic research.
• Diagnostic Probe Development: Incorporated into nucleic acid probes to enhance stability and specificity for applications in fluorescence in situ hybridization (FISH) and PCR-based diagnostics.
• Biochemical Tool Manufacturing: Employed in the production of enzyme substrates, inhibitors, and other research reagents for studying nucleic acid-interacting proteins.

Basic Information

Product Name	1-(β-D-Xylofuranosyl)-5-Methylcytosine
CAS No.	18492-10-9
Molecular Formula	C10H15N3O5
Molecular Weight	257.24 g/mol
Synonyms	5-Methylcytidine Xyloside; 5-Methyl-1-β-D-xylofuranosylcytosine; 5-Methylcytosine β-D-xylofuranoside; 1-β-D-Xylofuranosyl-5-methylcytosine; 5-Methylcytosine-1-β-D-xyloside; 5-MC-Xyl; Xylosyl-5-methylcytosine
EINECS	Contact for details

Quality Control

Our 1-(β-D-Xylofuranosyl)-5-Methylcytosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.