Description

Furanomycin is a naturally occurring, non-proteinogenic amino acid antibiotic with a unique furan ring structure. This compound is of significant interest in biochemical and pharmaceutical research due to its potent antimicrobial properties and its role as a mechanism-based inhibitor of aminoacyl-tRNA synthetases. It serves as a critical tool for researchers in microbiology, enzymology, and medicinal chemistry, enabling the study of protein synthesis, antibiotic resistance, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a selective inhibitor to study the function and mechanism of isoleucyl-tRNA synthetase and other aminoacyl-tRNA synthetases in protein biosynthesis.
• Antimicrobial Studies: Employed as a reference standard in assays to investigate its spectrum of activity against various bacterial strains and to explore mechanisms of antibiotic action.
• Medicinal Chemistry: Serves as a unique scaffold or lead compound for the design and synthesis of novel antibiotics targeting bacterial protein synthesis.
• Enzyme Kinetics: Utilized in kinetic studies to determine inhibition constants (Ki) and understand the interaction between antibiotics and their enzymatic targets.
• Microbiology: Applied in laboratory settings to study bacterial growth inhibition, resistance development, and the genetics of antibiotic production.

Basic Information

Product Name	Furanomycin
CAS No.	18455-25-9
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(2S,3S,4R)-2-Amino-3,4-dihydroxy-3,4-dihydro-2H-furan-5-carboxylic acid; L-(+)-Furanomycin; NSC 163049; Antibiotic 696; 2-Amino-2,3-dideoxy-D-erythro-hex-2-enonic acid 1,4-lactone
EINECS	Contact for details

Quality Control

Our Furanomycin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.