Description

Penitricin B is a polyene macrolide antibiotic complex, a critical pharmaceutical intermediate and reference standard. This compound is valued for its potent antifungal activity, particularly against *Candida* species, making it essential for research and development in antimicrobial therapies. It is primarily utilized by pharmaceutical manufacturers, research institutions, and quality control laboratories involved in developing and testing antifungal drugs and APIs.

Application

• Pharmaceutical Intermediate: Serves as a key starting material or precursor in the synthesis of advanced antifungal medications, including nystatin and related polyene antibiotics.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control, method validation, and assay calibration of antifungal products.
• Microbiological Research: Employed in in-vitro studies to investigate mechanisms of action, resistance patterns, and efficacy spectra against various fungal pathogens.
• API Manufacturing: Integral to the production chain of active pharmaceutical ingredients (APIs) for topical and oral antifungal formulations.
• Veterinary Medicine: Applied in the development of antifungal treatments for animal health.

Basic Information

Product Name	Penitricin B
CAS No.	18445-71-1
Molecular Formula	C61H89NO20
Molecular Weight	1164.36 g/mol
Synonyms	Penitricin B; A-28695B; Antibiotic A-28695B; Fungimycin; Levorin A2; Polyfungin B; (8E,10E,12E,14E,16E,18E,20E,22E,24E,26E,28E,30E,32E,34E,36E)-36-[(6-Deoxy-4-O-(2,6-dideoxy-4-O-[(1S)-1-hydroxyethyl]-β-D-arabino-hexopyranosyl)-β-D-mannopyranosyl]oxy]-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35-octadecahydroxy-38-methyl-13,15-dioxo-12,16-dioxa-2,4-diazanonatriaconta-8,10,12,14,16,18,20,22,24,26,28,30,32,34,36-pentaen-39-oic Acid
EINECS	Contact for details

Quality Control

Our Penitricin B is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates and reference standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.