Description

Dgtp Hydrate Sodium Salt is a high-purity biochemical reagent essential for nucleotide synthesis and molecular biology research. This compound serves as a critical building block in enzymatic and chemical processes, offering reliable performance and consistent quality. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers requiring precise and stable nucleotide precursors for their workflows.

Application

• Nucleotide Synthesis: Acts as a key substrate in the enzymatic synthesis of deoxyguanosine triphosphate (dGTP) and related nucleotides.
• PCR & Molecular Diagnostics: Used in the formulation of reagent mixes for polymerase chain reaction (PCR) and other nucleic acid amplification techniques.
• Biochemical Research: Essential for studies involving DNA polymerases, reverse transcriptases, and other enzymes that utilize nucleotide substrates.
• Pharmaceutical Development: Employed in the research and production of antiviral drugs, gene therapies, and other nucleotide-based therapeutics.
• Sequencing Technologies: A component in next-generation sequencing (NGS) workflows and Sanger sequencing reactions.
• Enzyme Kinetics Studies: Used to investigate enzyme mechanisms and measure kinetic parameters of nucleic acid polymerizing enzymes.

Basic Information

Product Name	Dgtp Hydrate Sodium Salt
CAS No.	18423-40-0
Molecular Formula	C10H14N5Na2O13P3 · xH2O
Molecular Weight	Anhydrous: 529.13 g/mol (Disodium salt)
Synonyms	2'-Deoxyguanosine-5'-triphosphate trisodium salt hydrate; dGTP Na salt; Deoxyguanosine triphosphate trisodium salt; 2'-Deoxy-GTP trisodium salt; dGTP trisodium salt; 2'-Deoxyguanosine 5'-(tetrahydrogen triphosphate) trisodium salt; Guanosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), trisodium salt
EINECS	Contact for details

Quality Control

Our Dgtp Hydrate Sodium Salt is manufactured under strict quality control protocols to ensure it meets the high standards required for sensitive biochemical applications. Each batch is tested for identity, purity, and absence of contaminating nucleases. A comprehensive Certificate of Analysis (COA) detailing HPLC purity, absorbance ratios, and bioburden is provided with every shipment to guarantee traceability and performance consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Anhydrous basis)
UV Absorbance (A250/A260)	0.80 - 0.90
UV Absorbance (A280/A260)	0.60 - 0.72
pH (1% Solution)	6.5 - 7.5
Water Content (KF)	≤ 10.0%
Endotoxin	< 10 EU/mg
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.