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4-Amino-7-β-D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid CAS NO 18418-00-3


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CAS No.:18418-00-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Amino-7-β-D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid is a key nucleoside derivative and a vital building block in synthetic organic chemistry and pharmaceutical research. This compound is essential for the development of novel antiviral and anticancer agents, particularly in the synthesis of modified nucleosides and nucleotides. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and cancer.
  • Antiviral Drug Research: Used in the development of experimental therapeutics against a range of DNA and RNA viruses.
  • Oncology Research: Serves as a building block for creating purine nucleoside analogs that interfere with cancer cell proliferation.
  • Biochemical Tool Compound: Employed in enzymatic studies and as a substrate or inhibitor for nucleoside-metabolizing enzymes.
  • Fine Chemical Synthesis: A specialized intermediate for constructing complex molecules in custom synthesis and process development.
  • Academic & Institutional Research: Used in university and government labs for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name 4-Amino-7-β-D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid
CAS No. 18418-00-3
Molecular Formula C₁₂H₁₄N₄O₇
Molecular Weight 326.26 g/mol
Synonyms 4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid; 4-Amino-5-carboxy-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 5-Carboxy-4-amino-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Amino-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid; 7H-Pyrrolo[2,3-d]pyrimidine-5-carboxylic acid, 4-amino-7-β-D-ribofuranosyl-; Carboxyaminoimidazole ribonucleotide (CAIR) analog; Nucleoside intermediate 18418-00-3
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Quality Control

Our 4-Amino-7-β-D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/IR) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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