Description

(5Beta)-3Beta-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-14-Hydroxycard-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of potent cardiovascular and anticancer agents, where structural precision is paramount. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic compounds, particularly those targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of specialized cardiac glycosides and related therapeutic agents.
• Biochemical Research: Used as a reference standard and active probe in studies of Na+/K+-ATPase inhibition and cardiac cell signaling pathways.
• Anticancer Drug Development: Serves as a starting material for the synthesis of novel compounds being investigated for their cytotoxic properties.
• Academic Research: Employed in university and institutional labs for pharmacological studies and structure-activity relationship (SAR) analysis.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	(5Beta)-3Beta-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-14-Hydroxycard-20(22)-Enolide
CAS No.	18404-43-8
Molecular Formula	C29H44O9
Molecular Weight	536.66 g/mol
Synonyms	Digitoxigenin β-D-digitoxoside; 3β-(Digitoxosyloxy)-14-hydroxy-5β-card-20(22)-enolide; 3β-O-(2,6-Dideoxy-β-D-ribo-hexopyranosyl)-14-hydroxy-5β-card-20(22)-enolide; Gitoxigenin β-D-digitoxoside; 3β-(Digitoxosyloxy)-14-hydroxyl-5β,20(22)-cardenolide; 14-Hydroxydigitoxigenin β-D-digitoxoside; 3β-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
EINECS	Contact for details

Quality Control

Our (5Beta)-3Beta-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-14-Hydroxycard-20(22)-Enolide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing including HPLC, NMR, and MS for identity confirmation and purity assessment. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture. For long-term storage, consider storing under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.