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2,3-Difluorobenzoyl Chloride CAS NO 18355-73-2
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CAS No.:18355-73-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,3-Difluorobenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of fluorine atoms and a highly reactive acyl chloride group, enabling precise molecular modifications. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty materials industries who require a reliable, high-quality intermediate for constructing complex fluorinated molecules.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing enhanced metabolic stability due to fluorination.
- Agrochemical Synthesis: Used in manufacturing advanced herbicides, fungicides, and pesticides where the difluorobenzoyl moiety contributes to biological activity and environmental persistence.
- Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic display materials, improving dielectric anisotropy and stability.
- Polymer Modification: Employed to introduce fluorinated benzoyl groups into polymer chains, enhancing material properties like chemical resistance, thermal stability, and surface characteristics.
- Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation, amide bond formation, and esterification reactions in research and fine chemical production.
- Fluorinated Dye & Pigment Intermediate: Used in the development of specialized dyes and pigments with unique light-fastness and color properties.
Basic Information
| Product Name | 2,3-Difluorobenzoyl Chloride |
| CAS No. | 18355-73-2 |
| Molecular Formula | C7H3ClF2O |
| Molecular Weight | 176.55 g/mol |
| Synonyms | 2,3-Difluorobenzoyl chloride; Benzoyl chloride, 2,3-difluoro-; 2,3-Difluorobenzoic acid chloride; o,m-Difluorobenzoyl Chloride; 2,3-DFBC; 2,3-Difluorobenzoylchloride; 2,3-Difluorobenzenecarbonyl chloride |
| EINECS | Contact for details |
Quality Control
Our 2,3-Difluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for our global B2B clients.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and alcohols.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (GC/HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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