Description

5α-Cholestane-3β,6β,16β,23,24-Pentaol is a high-purity, polyhydroxylated sterol derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical reference standard and synthetic intermediate for the study of sterol metabolism, membrane biophysics, and the synthesis of complex bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on steroid chemistry, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of sterol-based compounds in drug development and quality control laboratories.
• Biochemical Research: Serves as a key intermediate or substrate in enzymatic studies, metabolic pathway investigations, and research into cholesterol biosynthesis and its regulation.
• Organic Synthesis: Acts as a versatile chiral building block for the semi-synthesis of complex natural products, novel steroid analogs, and potential pharmacologically active molecules.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic chemistry, stereochemistry, and the physical properties of polyhydroxylated steroids.
• Analytical Method Development: Utilized to develop and validate chromatographic methods (HPLC, GC) and spectroscopic techniques for sterol analysis in various matrices.

Basic Information

Product Name	5α-Cholestane-3β,6β,16β,23,24-Pentaol
CAS No.	18206-50-3
Molecular Formula	C₂₇H₄₈O₅
Molecular Weight	452.67 g/mol
Synonyms	5α-Cholestane-3β,6β,16β,23,24-pentol; (3β,5α,6β,16β)-Cholestane-3,6,16,23,24-pentaol; 3β,6β,16β,23,24-Pentahydroxy-5α-cholestane; Cholestanepentaol
EINECS	Contact for details

Quality Control

Our 5α-Cholestane-3β,6β,16β,23,24-Pentaol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, IR and NMR for structural confirmation, and specific tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.