Description

C(14A)-Homo-27-Norgammacerane-3β,21α-Diol is a high-purity, specialized triterpenoid derivative with a defined stereochemistry at the 3-beta and 21-alpha positions. This compound is valued for its role as a critical advanced intermediate in the synthesis of complex bioactive molecules and for use in pharmaceutical research and development. It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-like therapeutics and hormone analogs.
• Biochemical Research: Used as a reference standard or probe in studies of enzyme inhibition, receptor binding, and metabolic pathways.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs targeting nuclear receptors and metabolic enzymes.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and natural product chemistry.
• Process Development: Utilized in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	C(14A)-Homo-27-Norgammacerane-3β,21α-Diol
CAS No.	18188-24-4
Molecular Formula	C30H52O2
Molecular Weight	444.7 g/mol
Synonyms	3β,21α-Dihydroxy-14α-homo-27-norgammacerane; 14α-Homo-27-norgammacerane-3β,21α-diol; (3β,21α)-14α-Homo-27-norgammacerane-3,21-diol; Gammacerane-3β,21α-diol derivative; Triterpenoid diol intermediate; 18188-24-4; 3,21-Dihydroxy-14-homo-27-norgammacerane
EINECS	Contact for details

Quality Control

Our C(14A)-Homo-27-Norgammacerane-3β,21α-Diol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is stable under these conditions but should be handled in a manner to minimize prolonged exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.