Description

Silicic Acid Di(tert-Butyl)Diethyl Ester is a specialized organosilicon compound, CAS NO 18151-86-5, valued for its role as a versatile chemical intermediate and protecting group in advanced synthesis. Its significance lies in its ability to introduce silicon-based functionalities or protect sensitive hydroxyl groups under demanding reaction conditions. This product is essential for pharmaceutical research, agrochemical development, and the synthesis of advanced materials, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules, particularly where silicon is incorporated for metabolic stability or as a synthetic handle.
• Agrochemical Synthesis: Serves as a key building block in creating novel pesticides, herbicides, and plant growth regulators with enhanced properties.
• Material Science Precursor: Acts as a precursor for silicon-containing polymers, resins, and hybrid organic-inorganic materials (ORMOSILs) with tailored thermal and mechanical properties.
• Cross-Coupling Reactions: Employed in palladium-catalyzed reactions, such as the Hiyama coupling, as an organosilicon reagent for carbon-carbon bond formation.
• Hydroxyl Group Protection: Functions as a protecting group for alcohols and diols in multi-step organic synthesis, offering stability under basic and nucleophilic conditions.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel silicon-based ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Silicic Acid Di(tert-Butyl)Diethyl Ester
CAS No.	18151-86-5
Molecular Formula	C12H28O4Si
Molecular Weight	264.44 g/mol
Synonyms	Di-tert-butyl diethyl orthosilicate; Di-tert-butylsilanediol diethyl ether; Tetraethyl di-tert-butyl orthosilicate; Silicic acid, tetraethyl ester, di-tert-butyl derivative; 1,1-Di-tert-butoxy-3,3-diethoxy-1,3-disiloxane; Di-tert-butoxydiethoxy silane; DTBDES; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Silicic Acid Di(tert-Butyl)Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.