Description

(20R,22R,24S)-2β,3β,14α,20,22,24-Hexahydroxy-5β-Cholesta-7-Ene-6-One is a highly functionalized steroidal compound of significant interest in advanced organic synthesis and pharmaceutical research. Its complex polyhydroxylated structure makes it a valuable chiral building block and a key intermediate for the development of novel bioactive molecules. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to explore new therapeutic pathways and synthesize complex natural product derivatives.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of complex steroid-based drugs and novel therapeutic agents.
• Biochemical Research: Used as a reference standard and a probe in metabolic pathway studies and enzyme interaction research due to its specific stereochemistry.
• Fine Chemical Synthesis: Acts as a versatile building block for the preparation of specialized steroidal compounds with modified biological activity.
• Natural Product Chemistry: Employed in the semi-synthesis or total synthesis of complex natural products that share its steroidal backbone.
• Process Development: Utilized in R&D for scaling up synthetic routes to complex polyhydroxylated steroids.

Basic Information

Product Name	(20R,22R,24S)-2β,3β,14α,20,22,24-Hexahydroxy-5β-Cholesta-7-Ene-6-One
CAS No.	18089-44-6
Molecular Formula	C₂₇H₄₄O₇
Molecular Weight	480.64 g/mol
Synonyms	2β,3β,14α,20,22,24-Hexahydroxycholest-7-en-6-one; (20R,22R,24S)-Hexahydroxy-5β-cholest-7-en-6-one; 5β-Cholest-7-ene-2β,3β,14α,20,22,24-hexol-6-one; Steroid polyol intermediate; Cholestane polyhydroxy ketone
EINECS	Contact for details

Quality Control

Our (20R,22R,24S)-2β,3β,14α,20,22,24-Hexahydroxy-5β-Cholesta-7-Ene-6-One is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when possible to prevent oxidation and moisture uptake. For long-term storage, consider desiccants and inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.