Description

(20R,25R)-Spirost-5-En-3Beta-Yl Acetate CAS NO 1061-54-7 is a high-purity steroidal sapogenin derivative, specifically the 3β-acetate of diosgenin. This compound serves as a critical pharmaceutical intermediate and a versatile building block in organic synthesis. It is essential for manufacturers and research institutions in the pharmaceutical, nutraceutical, and fine chemical sectors requiring a reliable, high-quality precursor for steroid-based APIs and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of steroidal drugs, including corticosteroids, sex hormones, and other bioactive steroids.
• Steroid Research: A fundamental reference standard and precursor in academic and industrial research focused on steroid chemistry and pharmacology.
• Nutraceutical Synthesis: Used in the production of steroidal sapogenin-based dietary supplements and health products.
• Fine Chemical Production: Serves as a chiral building block for the synthesis of complex organic molecules in asymmetric synthesis.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, TLC, or GC analysis.

Basic Information

Product Name	(20R,25R)-Spirost-5-En-3Beta-Yl Acetate
CAS No.	1061-54-7
Molecular Formula	C29H44O4
Molecular Weight	456.66 g/mol
Synonyms	Diosgenin Acetate; (25R)-Spirost-5-en-3β-yl acetate; 3β-Hydroxyspirost-5-en-3-yl acetate; (3β,25R)-Spirost-5-en-3-yl acetate; Diosgenin 3-acetate; 25R-Diosgenin acetate; Tigogenin acetate (Note: related but check isomer); Smilagenin acetate (Note: related but check isomer)
EINECS	213-332-0

Quality Control

Our (20R,25R)-Spirost-5-En-3Beta-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets stringent specifications for use as a pharmaceutical intermediate. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	195°C - 205°C
Specific Rotation	-110° to -120° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.