Description

3β,16β,23,24-Tetrahydroxy-5α-Cholestan-6-One is a high-purity, multi-hydroxylated steroidal ketone of significant research interest. This compound serves as a critical intermediate and reference standard in the synthesis and study of complex steroid derivatives and bile acids. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on steroid chemistry. Its defined structure makes it valuable for metabolic pathway studies and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of more complex steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic research, and investigations into cholesterol biosynthesis pathways.
• Academic & Discovery Chemistry: Serves as a starting material for novel organic synthesis, enabling the exploration of new chemical entities in steroid chemistry.
• Analytical Standard: Employed in analytical methods such as HPLC and LC-MS for method development, validation, and quality control of related steroid compounds.
• Fine Chemical Synthesis: Intermediate for producing specialized steroidal compounds used in various high-value chemical applications.

Basic Information

Product Name	3β,16β,23,24-Tetrahydroxy-5α-Cholestan-6-One
CAS No.	18089-15-1
Molecular Formula	C₂₇H₄₆O₅
Molecular Weight	450.66 g/mol
Synonyms	3β,16β,23,24-Tetrahydroxy-5α-cholestan-6-one; (3β,5α,16β)-3,16,23,24-Tetrahydroxycholestan-6-one; 5α-Cholestane-3β,16β,23,24-tetrol-6-one; 6-Keto-3β,16β,23,24-tetrahydroxy-5α-cholestane; Tetrahydroxycholestanone
EINECS	Contact for details

Quality Control

Our 3β,16β,23,24-Tetrahydroxy-5α-Cholestan-6-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC, to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions. For long-term storage, consider using an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.