Description

Sodium Trimethylsilanolate is a highly reactive organosilicon compound that serves as a versatile intermediate and reagent in advanced chemical synthesis. Its value lies in its ability to act as a potent nucleophile and a source of the trimethylsilanolate anion, enabling the introduction of silyl groups and facilitating deprotonation reactions under mild conditions. This product is essential for manufacturers in the pharmaceutical, agrochemical, and specialty silicone industries, where it is used to create novel compounds, protect sensitive functional groups, and modify material surfaces.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing moieties or as a protecting group reagent.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its reactivity aids in creating complex molecular structures.
• Silicone Polymer Modification: Acts as a chain terminator or cross-linking agent in the production of specialty silicone oils, resins, and elastomers.
• Surface Silylation Agent: Employed to modify the surface properties of inorganic materials like silica, glass, and metals, enhancing hydrophobicity or compatibility with organic matrices.
• Catalyst and Reagent: Utilized as a strong base in organic synthesis for deprotonation reactions and as a catalyst component in various polymerization processes.
• Laboratory Research: Serves as a valuable reagent in R&D for exploring new organosilicon chemistry and material science applications.

Basic Information

Item	Details
Product Name	Sodium Trimethylsilanolate
CAS No.	18027-10-6
Molecular Formula	C3H9NaOSi
Molecular Weight	112.18 g/mol
Synonyms	Sodium Trimethylsilanolate; Trimethylsilanol Sodium Salt; Sodium Trimethylsiloxide; Sodium (Trimethylsilyl)oxide; Sodium O-Trimethylsilylate; NaOSi(CH3)3; Trimethylsilyl Sodium; Sodium Silanolate, Trimethyl-
EINECS	241-979-1

Quality Control

Our Sodium Trimethylsilanolate is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support compliance with global regulatory frameworks including REACH. Specifications can be tailored to meet specific customer requirements for research or industrial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the material must be stored under a dry, inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed when not in use to prevent degradation from atmospheric moisture and carbon dioxide. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or lumps
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0 %
Solubility	Soluble in common organic solvents (e.g., THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.