Description

2,5(10)-Estradien-3-Ol-17-One 3-Methyl Ether CAS NO 17976-32-8 is a high-purity steroid derivative, specifically a methylated form of a key estradienone intermediate. This compound is of significant commercial importance as a critical building block in the synthesis of more complex steroidal pharmaceuticals and active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of hormone-based therapies and other specialized organic compounds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of steroidal drugs and hormones.
• Research & Development: Used in academic and industrial laboratories for the study of steroid chemistry and the development of new therapeutic agents.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex organic molecules with specific stereochemistry.
• API Manufacturing: Employed in the controlled synthesis of Active Pharmaceutical Ingredients (APIs) requiring high-purity steroid backbones.
• Biochemical Research: Utilized in studies investigating steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	2,5(10)-Estradien-3-Ol-17-One 3-Methyl Ether
CAS No.	17976-32-8
Molecular Formula	C20H28O2
Molecular Weight	300.44 g/mol
Synonyms	3-Methoxyestra-2,5(10)-dien-17-one; 3-Methoxy-19-nor-17α-pregna-2,5(10)-dien-20-yn-17-ol; 3-Methoxyestra-2,5(10),16-trien-17-one (related isomer); 3-Methoxy-19-norpregna-2,5(10)-dien-20-yn-17-ol; 17-Keto-3-methoxyestra-2,5(10)-diene; Estra-2,5(10)-dien-17-one, 3-methoxy-; 3-Methyl Ether of 2,5(10)-Estradien-3-ol-17-one
EINECS	Contact for details

Quality Control

Our 2,5(10)-Estradien-3-Ol-17-One 3-Methyl Ether is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.