Description

6-(Trimethylsilylamino)-7-(Trimethylsilyl)-7H-Purine is a high-purity, silylated purine derivative of significant interest in advanced organic synthesis. This compound serves as a critical protected intermediate or building block, enabling the development of complex nucleoside analogs and pharmaceutical agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside-based drugs, including antiviral and anticancer agents.
• Agrochemical Research: Used in developing new pesticide and herbicide candidates with modified biological activity.
• Nucleoside Chemistry: Acts as a protected precursor for the preparation of modified purines and their conjugates in medicinal chemistry.
• Bioconjugation & Labeling: Potential use in creating labeled probes or modified biomolecules for diagnostic and research applications.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for specialty chemicals requiring silyl-protected amino groups.
• Academic & R&D: Serves as a valuable reagent in university and corporate research laboratories for exploring new synthetic methodologies.

Basic Information

Item	Detail
Product Name	6-(Trimethylsilylamino)-7-(Trimethylsilyl)-7H-Purine
CAS No.	17963-53-0
Molecular Formula	C11H21N5Si2
Molecular Weight	279.49 g/mol
Synonyms	6-(Trimethylsilylamino)-7-(trimethylsilyl)-7H-purine; 7H-Purine, 6-(trimethylsilylamino)-7-(trimethylsilyl)-; 6-Amino-7-(trimethylsilyl)-7H-purine, N-(trimethylsilyl)-; 6-(Trimethylsilylamino)-7-trimethylsilylpurine; 6-TMS-amino-7-TMS-purine; N-(Trimethylsilyl)-6-amino-7-(trimethylsilyl)-7H-purine; 17963-53-0; 6-Amino-7-(trimethylsilyl)purine, bis(trimethylsilyl) derivative
EINECS	Contact for details

Quality Control

Our 6-(Trimethylsilylamino)-7-(Trimethylsilyl)-7H-Purine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.