Description

Diethyl(Trimethylsilylmethyl)Malonate is a versatile organosilicon building block and a key reagent in advanced organic synthesis. Its unique structure, featuring a malonate ester core with a trimethylsilylmethyl group, makes it an essential precursor for the construction of complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as homologation reactions and the synthesis of silicon-containing intermediates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in carbon chain extension and homologation reactions.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its silicon moiety can influence biological activity and stability.
• Organosilicon Chemistry: Serves as a key reagent for introducing the trimethylsilylmethyl functional group into target molecules, enabling further transformations.
• Advanced Material Precursor: Employed in the research and development of specialty polymers and silicon-based materials with tailored properties.
• Organic Synthesis Reagent: Facilitates various carbon-carbon bond-forming reactions, including alkylations and Michael additions, in complex molecule assembly.
• Process Chemistry & Scale-up: Valued in process R&D for developing efficient, scalable synthetic routes to high-value chemical targets.

Basic Information

Product Name	Diethyl(Trimethylsilylmethyl)Malonate
CAS No.	17962-38-8
Molecular Formula	C11H22O4Si
Molecular Weight	246.38 g/mol
Synonyms	Diethyl (Trimethylsilyl)methylmalonate; (Trimethylsilylmethyl)malonic Acid Diethyl Ester; Diethyl (Trimethylsilylmethyl)propanedioate; Malonic Acid, (Trimethylsilylmethyl)-, Diethyl Ester; Diethyl (Trimethylsilylmethyl)malonate; Propanedioic Acid, (Trimethylsilylmethyl)-, 1,3-Diethyl Ester; Diethyl (Trimethylsilyl)methylmalonate
EINECS	Contact for details

Quality Control

Our Diethyl(Trimethylsilylmethyl)Malonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.