Description

(25S)-5β-Spirostane-1β,3β,4β,5-Tetrol is a high-purity, multi-hydroxylated spirostane derivative, a key structural motif in steroid chemistry. Its precise stereochemistry and functional group arrangement make it a valuable intermediate for the synthesis of complex bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel steroid drugs, hormone analogs, and other bioactive compounds.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control of related substances.
• Biochemical Research: Serves as a precursor or substrate in enzymatic studies, metabolic pathway investigations, and structure-activity relationship (SAR) studies of steroidal compounds.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, specialty chemicals, and advanced materials requiring a defined spirostane core.
• Academic & R&D: Utilized in university and institutional research for exploring new chemical reactions, catalysis, and the development of synthetic methodologies.

Basic Information

Product Name	(25S)-5β-Spirostane-1β,3β,4β,5-Tetrol
CAS No.	17934-59-7
Molecular Formula	C27H44O6
Molecular Weight	464.64 g/mol
Synonyms	1β,3β,4β,5-Tetrahydroxy-5β-spirostan-25S-ol; (25S)-Spirostane-1β,3β,4β,5-tetrol; 5β-Spirostane-1β,3β,4β,5-tetrol, (25S)-; 1β,3β,4β,5-Tetrahydroxyspirostan-25S-ol; Tigogenin tetrol (specific isomer); Neotigogenin tetrol derivative; Spirostanetetrol
EINECS	Contact for details

Quality Control

Our (25S)-5β-Spirostane-1β,3β,4β,5-Tetrol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (25S)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.