Description

(8α)-3-Methoxy-14β-Hydroxyestra-1,3,5(10),9(11)-Tetrene-17-One is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its specific structural configuration, which makes it a crucial building block for the synthesis of more complex steroidal molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for exploring new drug candidates and metabolic pathways.
• Hormone Analog Synthesis: A key building block for the development of novel estrogen or other steroid hormone analogs with potential therapeutic applications.
• Biochemical Research: Employed in academic and industrial laboratories to study steroid receptor interactions and enzyme inhibition mechanisms.
• Process Development: Used in scaling up and optimizing synthetic routes for the commercial production of steroidal compounds.

Basic Information

Product Name	(8α)-3-Methoxy-14β-Hydroxyestra-1,3,5(10),9(11)-Tetrene-17-One
CAS No.	17908-45-1
Molecular Formula	C19H24O3
Molecular Weight	300.39 g/mol
Synonyms	14β-Hydroxy-3-methoxyestra-1,3,5(10),9(11)-tetraen-17-one; 3-Methoxy-14β-hydroxyestra-1,3,5(10),9(11)-tetraen-17-one; 8α-Estrone derivative; 14β-Hydroxy-3-methoxy-8α-estra-1,3,5(10),9(11)-tetraen-17-one; 17908-45-1; Steroid intermediate 17908-45-1
EINECS	Contact for details

Quality Control

Our (8α)-3-Methoxy-14β-Hydroxyestra-1,3,5(10),9(11)-Tetrene-17-One is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.