Description

2,2-Di(Acetoxymethyl)Propionyl Chloride is a highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, which allows for the simultaneous introduction of both protected diol and acid chloride functionalities, enabling efficient multi-step transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), prodrugs, and complex polymer precursors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, prodrugs, and active pharmaceutical ingredients (APIs).
• Polymer Chemistry: Monomer or cross-linking agent for producing specialty polymers, resins, and coatings with tailored properties.
• Prodrug Synthesis: Used to create bioreversible derivatives of drugs to improve bioavailability, stability, or targeting.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex organic compounds, fragrances, and agrochemicals.
• Bioconjugation: Potential reagent for modifying biomolecules (e.g., peptides, sugars) due to its reactive acid chloride group.
• Material Science: Precursor for advanced materials and dendritic structures requiring controlled functionalization.

Basic Information

Product Name	2,2-Di(Acetoxymethyl)Propionyl Chloride
CAS No.	17872-59-2
Molecular Formula	C9H13ClO5
Molecular Weight	236.65 g/mol
Synonyms	2,2-Bis(acetoxymethyl)propionyl chloride; 3,3-Bis(acetoxymethyl)butanoyl chloride; 2,2-Di(acetoxymethyl)propanoic acid chloride; Pentaerythritol diacetate monochloride; 2,2-Bis(acetyloxymethyl)propanoyl chloride; 3,3-Bis(acetyloxymethyl)butyryl chloride; 1,3-Diacetoxy-2-(chlorocarbonyl)-2-methylpropane
EINECS	Contact for details

Quality Control

Our 2,2-Di(Acetoxymethyl)Propionyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including assay by titration and impurity profiling, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.