Description

2-Bromobenzyl Isothiocyanate is a versatile and reactive organosulfur compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a highly electrophilic isothiocyanate group, makes it a valuable precursor for constructing complex heterocycles and functionalized molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting cancer, inflammation, and infectious diseases.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by acting as a core scaffold for bioactive molecules.
• Chemical Biology Probe: Serves as a reactive handle for bioconjugation and labeling of proteins or other biomolecules due to the isothiocyanate group's affinity for amines.
• Heterocyclic Chemistry: Essential building block for the construction of benzothiazine, quinazoline, and other nitrogen-sulfur containing heterocycles.
• Material Science: Investigated as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	2-Bromobenzyl Isothiocyanate
CAS No.	17863-40-0
Molecular Formula	C8H6BrNS
Molecular Weight	228.11 g/mol
Synonyms	1-(Bromomethyl)-2-bromobenzene isothiocyanate; (2-Bromophenyl)methyl isothiocyanate; 2-Bromo-α-isothiocyanatotoluene; o-Bromobenzyl isothiocyanate; NSC 163063; 2-Bromobenzyl mustard oil; Isothiocyanic acid, (2-bromobenzyl) ester; (2-Bromobenzyl)isothiocyanate
EINECS	Contact for details

Quality Control

Our 2-Bromobenzyl Isothiocyanate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and other relevant physicochemical tests. A detailed Certificate of Analysis (COA) documenting purity, identity, and safety parameters is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents and amines. The container must be kept tightly closed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.