Description

3-Cyanopropanoyl Chloride is a versatile and highly reactive organic acid chloride derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in its bifunctional nature, combining a reactive acyl chloride group with a nitrile moiety, enabling efficient chain extension and the introduction of cyanoalkyl functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), advanced intermediates, and functional polymers.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of various drug molecules, particularly those requiring cyanoalkyl side chains or amide linkages.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where it acts as a linker to introduce specific bioactive groups.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored properties like thermal stability or specific reactivity.
• Fine Chemical Production: Employed in the multistep synthesis of complex organic compounds, dyes, and liquid crystals.
• Peptide Mimetics & Bioconjugation: Useful for modifying peptides or biomolecules by introducing the cyano-propionyl group.
• Material Science Research: Acts as a reagent for surface functionalization and the development of novel organic materials.

Basic Information

Product Name	3-Cyanopropanoyl Chloride
CAS No.	17790-82-8
Molecular Formula	C4H4ClNO
Molecular Weight	117.53 g/mol
Synonyms	4-Chloro-4-oxobutanenitrile; Succinonitrile monochloride; 3-Cyanopropionic acid chloride; β-Cyanopropionyl chloride; Butanenitrile, 4-chloro-4-oxo-; 4-Cyanobutanoyl chloride; NSC 9375
EINECS	241-772-5

Quality Control

Our 3-Cyanopropanoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment, ensuring compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize degradation and volatility. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from heat, sparks, open flames, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.