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3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-11β,14,19-Trihydroxy-5α-Card-20(22)-Enolide CAS NO 17669-76-0
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CAS No.:17669-76-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-11β,14,19-Trihydroxy-5α-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical research and development. Its value lies in its specific structural configuration, which is essential for studying and developing novel therapeutic agents targeting cardiovascular functions. This compound is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on cardiology and steroid-based drug discovery.
Application
- Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in drug manufacturing.
- Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the production of specialized cardiac glycoside-based therapeutics.
- Biochemical Research: Used in pharmacological studies to investigate mechanisms of action related to sodium-potassium ATPase inhibition.
- Drug Discovery & Development: Employed as a building block in medicinal chemistry for creating new molecular entities with potential cardiotonic activity.
- Analytical Testing: Utilized in HPLC, LC-MS, and NMR as a high-purity calibrant or internal standard for accurate quantification.
Basic Information
| Product Name | 3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-11β,14,19-Trihydroxy-5α-Card-20(22)-Enolide |
| CAS No. | 17669-76-0 |
| Molecular Formula | C29H44O10 |
| Molecular Weight | 552.66 g/mol |
| Synonyms | 19-Hydroxycannogenin 3-O-6-deoxy-α-L-mannopyranoside; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-11β,14,19-trihydroxy-5α-card-20(22)-enolide; Cannogenin α-L-6'-deoxy-mannoside; 6'-Deoxy-α-L-mannosyl cannogenin; 19-Hydroxycannogenin α-L-6-deoxymannoside; 3-O-(6-Deoxy-α-L-mannopyranosyl)-11β,14,19-trihydroxy-5α-card-20(22)-enolide |
| EINECS | Contact for details |
Quality Control
Our 3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-11β,14,19-Trihydroxy-5α-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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