Description

8-(n-Fluoren-2-Ylamino)-2'-Deoxyguanosine 5'-Monophosphate is a modified nucleotide monophosphate derivative, specifically a guanosine analog bearing a fluorenylamino group. This compound is of significant value as a critical intermediate and research reagent in the development of advanced molecular probes and therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on nucleic acid chemistry, targeted drug delivery, and diagnostic assay development.

Application

• Pharmaceutical Research: As a key building block in the synthesis of novel nucleoside-based prodrugs and antiviral/anticancer agents.
• Molecular Probe Development: For creating fluorescently labeled or otherwise tagged nucleotides used in DNA sequencing, hybridization assays, and real-time PCR.
• Bioconjugation Chemistry: Serving as a reactive intermediate for attaching oligonucleotides to other molecules, surfaces, or nanoparticles for diagnostic and therapeutic applications.
• Enzyme Substrate Studies: Used in biochemical assays to study the activity and inhibition of kinases, polymerases, and other nucleotide-processing enzymes.
• Academic Research: Fundamental studies in nucleic acid structure, function, and metabolism, particularly involving modified nucleosides.
• Diagnostic Kit Manufacturing: As a specialized raw material in the production of high-sensitivity diagnostic kits and reagents.

Basic Information

Product Name	8-(n-Fluoren-2-Ylamino)-2'-Deoxyguanosine 5'-Monophosphate
CAS No.	17660-46-7
Molecular Formula	C23H21N6O7P
Molecular Weight	524.42 g/mol
Synonyms	8-(2-Fluorenylamino)-2'-deoxyguanosine 5'-monophosphate; 8-(9H-Fluoren-2-ylamino)-2'-deoxyguanosine 5'-monophosphate; 2'-Deoxy-8-(fluoren-2-ylamino)guanosine 5'-monophosphate; 8-(2-Fluorenylamino)-dGMP; F-dGMP; 8-Fluorenylamino-dGMP; Modified dGMP; Nucleotide Fluorenylamino Derivative
EINECS	Contact for details

Quality Control

Our 8-(n-Fluoren-2-Ylamino)-2'-Deoxyguanosine 5'-Monophosphate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to ensure stability. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in DMSO, sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.