Description

Adonitoxin is a potent cardiac glycoside compound of significant interest in pharmaceutical research and development. Its specific molecular structure underpins its bioactivity, making it a valuable reference standard and a key intermediate for specialized synthesis. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors. We supply high-purity Adonitoxin to support critical applications in drug discovery and analytical method development.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of cardiac glycosides in drug formulations and raw materials via HPLC, LC-MS, or TLC.
• Biochemical Research: Serves as a crucial tool in pharmacological studies investigating the mechanisms of action of cardiotonic steroids on sodium-potassium ATPase.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed as a high-purity building block in the synthesis of more complex cardiac therapeutic agents.
• Quality Control & Method Development: Essential for developing, validating, and calibrating analytical methods in pharmaceutical QC/QA laboratories.
• Academic Research: Used in university and institutional labs for studies related to cardiovascular physiology, toxicology, and natural product chemistry.

Basic Information

Item	Detail
Product Name	Adonitoxin
CAS No.	17651-61-5
Molecular Formula	C29H42O10
Molecular Weight	550.64 g/mol
Synonyms	Adonitoxin; 3β,5β,14β-Trihydroxy-19-oxocard-20(22)-enolide 3-(6-deoxy-α-L-mannopyranoside); Adonitoxoside; Adonitoxol rhamnoside; Strophanthidin 3-O-α-L-rhamnoside; NSC 407324; Adonitoxine
EINECS	Contact for details

Quality Control

Our Adonitoxin is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.