Description

Lanatoside A is a specific cardiac glycoside compound, a key intermediate in the biosynthesis of digoxin and other related therapeutic agents. Its precise chemical structure makes it an essential reference standard and a critical starting material for pharmaceutical research and development. This high-purity compound is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in cardiovascular drug discovery, quality control, and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of cardiac glycosides in drug substances and finished products via HPLC, LC-MS, or TLC.
• Biochemical Research: Serves as a crucial intermediate in studies investigating the biosynthesis, metabolism, and structure-activity relationships (SAR) of digitalis glycosides.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a key precursor in the semi-synthetic production of digoxin and other cardiocative drugs.
• Analytical Method Development: Employed for developing and validating analytical methods in pharmacopeial compliance testing and impurity profiling.
• Metabolite Studies: Used in in vitro and in vivo studies to understand the metabolic pathways and pharmacokinetics of cardiac glycosides.

Basic Information

Product Name	Lanatoside A
CAS No.	17575-20-1
Molecular Formula	C49H76O20
Molecular Weight	985.1 g/mol
Synonyms	Lanatoside A; 12β-Hydroxydigoxin; Digilanide A; (3β,5β,12β)-3-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide; Lanatoside C Aglycone Triacetate; Digitalis lanata glycoside A
EINECS	Contact for details

Quality Control

Our Lanatoside A is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.