Description

2,2,2-Trifluoro-1-(Naphthalen-1-Yl)Ethanol is a fluorinated chiral alcohol building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of a naphthyl group and a trifluoroethanol moiety, which imparts distinct electronic and steric properties to target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly where fluorine substitution is desired for metabolic stability or bioavailability.
• Agrochemical Synthesis: Used in constructing advanced intermediates for novel pesticides and herbicides, leveraging the biological activity often associated with fluorinated compounds.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Specialty Material Precursor: Employed in the synthesis of monomers or additives for advanced polymers and liquid crystalline materials.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new fluorination strategies and structure-activity relationships.

Basic Information

Product Name	2,2,2-Trifluoro-1-(Naphthalen-1-Yl)Ethanol
CAS No.	17556-44-4
Molecular Formula	C₁₂H₉F₃O
Molecular Weight	226.19 g/mol
Synonyms	1-(1-Naphthyl)-2,2,2-trifluoroethanol; α-(Trifluoromethyl)-1-naphthalenemethanol; 1-Naphthyltrifluoromethylcarbinol; (1-Naphthyl)(trifluoromethyl)methanol; 2,2,2-Trifluoro-1-(1-naphthyl)ethanol; 1-(1-Naphthalenyl)-2,2,2-trifluoroethanol; 2,2,2-Trifluoro-1-naphthalen-1-ylethanol
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(Naphthalen-1-Yl)Ethanol is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay (by HPLC or GC), chiral purity (if applicable), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.