Description

1-(4-Methoxyphenyl)-2,2,2-Trifluoroethanol is a versatile fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a methoxy-substituted phenyl ring and a trifluoroethanol moiety, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Monomer: Employed in the development of specialty polymers with unique surface properties, chemical resistance, or optical characteristics.
• Chiral Auxiliary & Ligand Synthesis: The alcohol functional group allows for derivatization into chiral ligands or auxiliaries for asymmetric catalysis.
• Fluorine Chemistry Research: A valuable standard and reagent for academic and industrial research exploring the effects of fluorine substitution on molecular properties.

Basic Information

Product Name	1-(4-Methoxyphenyl)-2,2,2-Trifluoroethanol
CAS No.	17556-42-2
Molecular Formula	C9H9F3O2
Molecular Weight	206.16 g/mol
Synonyms	4-Methoxy-α-(trifluoromethyl)benzyl alcohol; (4-Methoxyphenyl)(trifluoromethyl)methanol; α,α,α-Trifluoro-4-methoxybenzyl alcohol; 1-(4-Methoxyphenyl)-2,2,2-trifluoroethan-1-ol; p-Methoxy-α-(trifluoromethyl)benzyl alcohol; 4-Methoxy-α,α,α-trifluorotoluene-α-ol; (4-Methoxyphenyl)trifluoromethyl carbinol
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxyphenyl)-2,2,2-Trifluoroethanol is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.