Description

Benzoyl Chloride, 5-Bromo-2-Hydroxy- is a versatile and highly reactive halogenated benzoyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of both the bromo and hydroxy substituents on the aromatic ring, enabling selective functionalization for the creation of complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with brominated aromatic structures, such as kinase inhibitors and antibacterial agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators where the bromo-hydroxy benzoyl moiety imparts specific biological activity.
• Liquid Crystal & OLED Material Production: Serves as a starting material for synthesizing brominated aromatic cores essential in electronic chemicals for displays and lighting.
• Polymer Modification: Acts as a reactive monomer or cross-linking agent for introducing aromatic ester and halogen functionalities into polymer backbones to alter thermal and physical properties.
• Dye & Pigment Manufacturing: Intermediate for producing brominated hydroxybenzophenone derivatives used as UV absorbers, photoinitiators, and colorants.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and esterification reactions to introduce the benzoyl group into complex molecular architectures under controlled conditions.

Basic Information

Product Name	Benzoyl Chloride, 5-Bromo-2-Hydroxy-
CAS No.	17464-66-3
Molecular Formula	C7H4BrClO2
Molecular Weight	235.46 g/mol
Synonyms	5-Bromo-2-hydroxybenzoyl chloride; 2-Hydroxy-5-bromobenzoyl chloride; 5-Bromosalicyloyl chloride; (5-Bromo-2-hydroxyphenyl)methanone chloride; 5-Bromo-2-hydroxybenzoic acid chloride
EINECS	Contact for details

Quality Control

Every batch of Benzoyl Chloride, 5-Bromo-2-Hydroxy- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.