Description

3-Pyridyl Isothiocyanate is a versatile heterocyclic building block and reagent characterized by its reactive isothiocyanate functional group attached to a pyridine ring. This compound matters for its critical role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel chemical entities, developing active ingredients, and creating specialized ligands or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the pyridyl moiety contributes to biological activity.
• Ligand and Chelator Preparation: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal complexation studies.
• Bioconjugation and Probe Development: The reactive isothiocyanate group enables coupling with amines, useful for labeling biomolecules or creating fluorescent probes.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic frameworks with specific electronic or binding properties.
• Chemical Biology Tool: Utilized to modify proteins or peptides to study biological pathways or create activity-based probes.

Basic Information

Product Name	3-Pyridyl Isothiocyanate
CAS No.	17452-27-6
Molecular Formula	C6H4N2S
Molecular Weight	136.17 g/mol
Synonyms	3-Isothiocyanatopyridine; 3-Pyridinyl isothiocyanate; β-Pyridyl isothiocyanate; m-Pyridyl isothiocyanate; Pyridine-3-isothiocyanate; 3-Pyridyl mustard oil; Isothiocyanic acid 3-pyridyl ester; 3-Pyridylisothiocyanate
EINECS	Contact for details

Quality Control

Our 3-Pyridyl Isothiocyanate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support its use in regulated research and development environments. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions. Protect from moisture to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.