Description

n-Succinyl-5-Aminoimidazole-4-Carboxamide Ribose is a key biochemical intermediate, specifically a purine biosynthesis precursor, essential for research and development in nucleotide chemistry. Its primary value lies in enabling the study of de novo purine synthesis pathways and serving as a critical building block for synthesizing more complex nucleoside analogs. This compound is vital for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly those focused on metabolic research, antiviral agents, and novel therapeutic development.

Application

• Biochemical Research: Critical intermediate for studying the de novo purine biosynthesis pathway in metabolic research.
• Pharmaceutical Development: Serves as a key precursor in the synthesis of novel nucleoside-based antiviral or anticancer agents.
• Enzymology Studies: Used as a substrate or inhibitor to investigate the function of enzymes like SAICAR synthetase within the purine biosynthetic cascade.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical and research laboratories.
• Metabolic Pathway Analysis: Utilized in cell culture and in vitro systems to trace and quantify purine metabolism and its dysregulation.
• Academic Research: Fundamental tool in university and institutional labs for fundamental biochemistry and molecular biology education and discovery.

Basic Information

Product Name	n-Succinyl-5-Aminoimidazole-4-Carboxamide Ribose
CAS No.	17388-80-6
Molecular Formula	C14H20N4O10
Molecular Weight	404.33 g/mol
Synonyms	SAICAR; Succinyl-AICAR; 5-Amino-1-(5-O-{[(2S,3S,4R,5R)-5-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,4-dihydroxyoxolan-2-yl]methyl}phosphonato)imidazole-4-carboxamide; 5'-Phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole; (S)-2-[5-Amino-1-(5-O-{[(2S,3S,4R,5R)-5-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,4-dihydroxyoxolan-2-yl]methyl}phosphonato)imidazole-4-carboxamido]succinic acid
EINECS	Contact for details

Quality Control

Our n-Succinyl-5-Aminoimidazole-4-Carboxamide Ribose is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic identification (NMR, MS). A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.