Description

α-Phenylcyclopentanecarbonyl Chloride is a versatile and reactive organic intermediate essential for advanced chemical synthesis. Its value lies in its role as a key acylating agent, enabling the efficient introduction of the α-phenylcyclopentanecarbonyl moiety into target molecules. This compound is critically needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motif can contribute to biological activity.
• Peptide Mimetics & PROTACs: Serves as a reagent for constructing complex organic molecules, including peptide analogs and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where its aromatic and alicyclic structure can influence material properties.
• Chemical Biology Probes: Acts as a derivatization agent for creating labeled compounds and molecular probes used in biochemical and cellular studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	α-Phenylcyclopentanecarbonyl Chloride
CAS No.	17380-62-0
Molecular Formula	C12H13ClO
Molecular Weight	208.68 g/mol
Synonyms	2-Phenylcyclopentanecarbonyl chloride; α-Phenylcyclopentanecarboxylic acid chloride; Cyclopentanecarbonyl chloride, 2-phenyl-; 2-Phenylcyclopentane-1-carbonyl chloride; (2-Phenylcyclopentyl)carbonyl chloride; 1-Chlorocarbonyl-2-phenylcyclopentane
EINECS	Contact for details

Quality Control

Our α-Phenylcyclopentanecarbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including purity by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.