Description

4-Amino-1-Pyrazolo[3,4-D]Pyrimidinyl 2'-Deoxyribonucleoside is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a key intermediate in the synthesis of novel therapeutic agents, particularly in the field of antiviral and anticancer drug discovery. It is essential for research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of nucleoside-based therapies and diagnostic probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and repair.
• Proteomics & Genomics: Employed in the development of molecular probes and tools for studying genetic expression and protein interactions.
• Antiviral Drug Development: Serves as a core scaffold for researching compounds active against viral polymerases.
• Oncology Research: Investigated for its potential incorporation into oligonucleotides designed for targeted cancer therapies.
• Diagnostic Reagent Synthesis: Used in creating labeled nucleotides for various diagnostic assays and imaging techniques.

Basic Information

Product Name	4-Amino-1-Pyrazolo[3,4-D]Pyrimidinyl 2'-Deoxyribonucleoside
CAS No.	17318-21-7
Molecular Formula	C10H12N6O4
Molecular Weight	280.24 g/mol
Synonyms	4-Amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl 2-deoxy-β-D-ribofuranoside; 4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine; 2'-Deoxy-4-aminopyrazolopyrimidine nucleoside; 4-APPdR; 4-Amino-pyrazolo-pyrimidine deoxyribonucleoside
EINECS	Contact for details

Quality Control

Our 4-Amino-1-Pyrazolo[3,4-D]Pyrimidinyl 2'-Deoxyribonucleoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.