Description

5'-Methylthioinosine is a modified nucleoside derivative of inosine, featuring a methylthio group at the 5' position. This structural modification makes it a valuable biochemical building block and research chemical for studying nucleoside metabolism and enzyme interactions. It is primarily utilized in pharmaceutical research, biochemical synthesis, and as a reference standard in analytical laboratories. The compound is supplied with a high level of purity to meet the stringent requirements of advanced scientific and industrial applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel nucleoside analogs with potential therapeutic activity.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for methyltransferase and nucleoside-metabolizing enzymes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other chromatographic techniques.
• Life Science Reagent: A component in cell culture media and diagnostic assay development for studying cellular processes.
• Chemical Synthesis: Acts as a specialized building block for the preparation of more complex molecules in medicinal chemistry.

Basic Information

Product Name	5'-Methylthioinosine
CAS No.	17298-58-7
Molecular Formula	C11H14N4O4S
Molecular Weight	298.32 g/mol
Synonyms	5'-Deoxy-5'-(methylthio)inosine; 5'-S-Methyl-5'-thioinosine; 6-Hydroxy-9-[(1-methylthio-1-deoxy-β-D-ribofuranosyl)purine]; 5'-Methylmercaptoinosine; 5'-MTI; Inosine, 5'-deoxy-5'-(methylthio)-; 5'-Deoxy-5'-methylthioinosine
EINECS	Contact for details

Quality Control

Our 5'-Methylthioinosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a Certificate of Analysis (COA) with every shipment, detailing all specification results to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.